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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
3
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pubmed:dateCreated |
1986-11-12
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pubmed:abstractText |
Ether stress applied at 10.00 h induced a 100% increase in serum prolactin in intact and ovariectomized androgenized rats. Ovariectomy significantly diminished the basal serum prolactin values observed in intact androgenized rats. Two doses of progesterone (5 mg) given to intact and ovariectomized androgenized rats 14 and 2 h before exposure to ether stress increased prolactin values in the control groups but completely prevented the effect of stress. Exposure to ether stress induced a 100% increase in serum prolactin values in androgenized rats with increased serum progesterone levels 4 days after the induction of ovulation and the luteal phase with human chorionic gonadotropin (hCG). A group of androgenized rats with induced maternal behaviour and which had been suckled for 6 days was given 100 i.u. hCG and suckled for another 6 days after the hCG-induced luteal phase had been established. The serum prolactin and progesterone values of these rats were significantly higher than those treated with hCG only and ether stress did not increase prolactin release. A greatly increased serum concentration of prolactin was obtained in pro-oestrous and oestrous virgin rats after exposure to ether stress. Serum prolactin was also increased by stress in male rats. Progesterone administration to these female and male rats prevented stress-induced prolactin release. To ascertain the part played by dopamine and serotonin in the effect of stress on prolactin release, groups of androgenized and oestrous female rats were treated with bromocriptine or p-chlorophenylalanine methylester hydrochloride (pCPA).(ABSTRACT TRUNCATED AT 250 WORDS)
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/4-chlorophenylalanine methyl ester,
http://linkedlifedata.com/resource/pubmed/chemical/Bromocriptine,
http://linkedlifedata.com/resource/pubmed/chemical/Chorionic Gonadotropin,
http://linkedlifedata.com/resource/pubmed/chemical/Fenclonine,
http://linkedlifedata.com/resource/pubmed/chemical/Progesterone,
http://linkedlifedata.com/resource/pubmed/chemical/Prolactin,
http://linkedlifedata.com/resource/pubmed/chemical/Testosterone
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pubmed:status |
MEDLINE
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pubmed:month |
Sep
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pubmed:issn |
0022-0795
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
110
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
423-8
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pubmed:dateRevised |
2008-11-21
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pubmed:meshHeading |
pubmed-meshheading:2944979-Animals,
pubmed-meshheading:2944979-Bromocriptine,
pubmed-meshheading:2944979-Chorionic Gonadotropin,
pubmed-meshheading:2944979-Estrus,
pubmed-meshheading:2944979-Female,
pubmed-meshheading:2944979-Fenclonine,
pubmed-meshheading:2944979-Male,
pubmed-meshheading:2944979-Ovariectomy,
pubmed-meshheading:2944979-Progesterone,
pubmed-meshheading:2944979-Prolactin,
pubmed-meshheading:2944979-Rats,
pubmed-meshheading:2944979-Rats, Inbred Strains,
pubmed-meshheading:2944979-Stress, Physiological,
pubmed-meshheading:2944979-Testosterone
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pubmed:year |
1986
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pubmed:articleTitle |
Stress-induced prolactin release in female, male and androgenized rats: influence of progesterone treatment.
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pubmed:publicationType |
Journal Article
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