Switch to
Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
5
|
pubmed:dateCreated |
1986-10-2
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pubmed:abstractText |
Two HLA-identical brothers developed Type 1 diabetes simultaneously. In the light of present knowledge of the pathogenesis of Type 1 diabetes, immunosuppression was adopted in one brother by means of white cell transfusion from the father. The other brother acted as a control. This immunosuppressive approach has been shown to be effective in kidney transplantation and, as far as Type 1 diabetes is concerned, in the BB Wistar rat. An immunological and metabolic follow-up study of 1 yr only revealed slight differences between the 2 brothers (who are both on insulin) but the pattern of lymphocyte activation appeared to become normalized earlier in the transfused brother.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
|
pubmed:month |
Jun
|
pubmed:issn |
0265-5985
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pubmed:author | |
pubmed:issnType |
Print
|
pubmed:volume |
3
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pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
273-6
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pubmed:dateRevised |
2011-11-17
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pubmed:meshHeading |
pubmed-meshheading:2943548-Adolescent,
pubmed-meshheading:2943548-Adult,
pubmed-meshheading:2943548-Blood Transfusion,
pubmed-meshheading:2943548-C-Peptide,
pubmed-meshheading:2943548-Diabetes Mellitus, Type 1,
pubmed-meshheading:2943548-Humans,
pubmed-meshheading:2943548-Immunity, Cellular,
pubmed-meshheading:2943548-Immunosuppression,
pubmed-meshheading:2943548-Insulin,
pubmed-meshheading:2943548-Leukocyte Transfusion,
pubmed-meshheading:2943548-Lymphocyte Activation,
pubmed-meshheading:2943548-Male,
pubmed-meshheading:2943548-T-Lymphocytes, Regulatory
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pubmed:year |
1986
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pubmed:articleTitle |
White cells transfusion in recent onset type 1 diabetes.
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pubmed:publicationType |
Journal Article,
Case Reports,
Research Support, Non-U.S. Gov't
|