Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2
pubmed:dateCreated
1986-3-21
pubmed:abstractText
The reversible binding of neocarzinostatin chromophore to polynucleotides was studied in order to understand the molecular basis of its base sequence-specificity in DNA damage production. Studies of the spectroscopic and thermodynamic properties of chromophore-polynucleotide interactions reveal that the binding of the chromophore to poly(dA-dT) is qualitatively and quantitatively different from that to poly(dG-dC) (and poly(dI-dC]. From these and other experiments using double-stranded mixtures of homopolynucleotides, it is proposed that the observed A T specific intercalation might result from differential recognition of minor variations in the B-DNA type structure by the chromophore.
pubmed:grant
pubmed:commentsCorrections
http://linkedlifedata.com/resource/pubmed/commentcorrection/2935786-151278, http://linkedlifedata.com/resource/pubmed/commentcorrection/2935786-189801, http://linkedlifedata.com/resource/pubmed/commentcorrection/2935786-2996589, http://linkedlifedata.com/resource/pubmed/commentcorrection/2935786-3000442, http://linkedlifedata.com/resource/pubmed/commentcorrection/2935786-3158880, http://linkedlifedata.com/resource/pubmed/commentcorrection/2935786-39562, http://linkedlifedata.com/resource/pubmed/commentcorrection/2935786-4000953, http://linkedlifedata.com/resource/pubmed/commentcorrection/2935786-4052380, http://linkedlifedata.com/resource/pubmed/commentcorrection/2935786-4808695, http://linkedlifedata.com/resource/pubmed/commentcorrection/2935786-5165064, http://linkedlifedata.com/resource/pubmed/commentcorrection/2935786-5492018, http://linkedlifedata.com/resource/pubmed/commentcorrection/2935786-6086935, http://linkedlifedata.com/resource/pubmed/commentcorrection/2935786-6101079, http://linkedlifedata.com/resource/pubmed/commentcorrection/2935786-6173064, http://linkedlifedata.com/resource/pubmed/commentcorrection/2935786-6223633, http://linkedlifedata.com/resource/pubmed/commentcorrection/2935786-6269057, http://linkedlifedata.com/resource/pubmed/commentcorrection/2935786-6273591, http://linkedlifedata.com/resource/pubmed/commentcorrection/2935786-6292854, http://linkedlifedata.com/resource/pubmed/commentcorrection/2935786-6327070, http://linkedlifedata.com/resource/pubmed/commentcorrection/2935786-6445563, http://linkedlifedata.com/resource/pubmed/commentcorrection/2935786-6448634, http://linkedlifedata.com/resource/pubmed/commentcorrection/2935786-6448635, http://linkedlifedata.com/resource/pubmed/commentcorrection/2935786-6456758, http://linkedlifedata.com/resource/pubmed/commentcorrection/2935786-6457635, http://linkedlifedata.com/resource/pubmed/commentcorrection/2935786-6626502, http://linkedlifedata.com/resource/pubmed/commentcorrection/2935786-6712932, http://linkedlifedata.com/resource/pubmed/commentcorrection/2935786-6866768, http://linkedlifedata.com/resource/pubmed/commentcorrection/2935786-6941276, http://linkedlifedata.com/resource/pubmed/commentcorrection/2935786-6953980, http://linkedlifedata.com/resource/pubmed/commentcorrection/2935786-7071016, http://linkedlifedata.com/resource/pubmed/commentcorrection/2935786-7071593, http://linkedlifedata.com/resource/pubmed/commentcorrection/2935786-7422003
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Jan
pubmed:issn
0305-1048
pubmed:author
pubmed:issnType
Print
pubmed:day
24
pubmed:volume
14
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
1089-105
pubmed:dateRevised
2009-11-18
pubmed:meshHeading
pubmed:year
1986
pubmed:articleTitle
Mode of reversible binding of neocarzinostatin chromophore to DNA: base sequence dependency of binding.
pubmed:publicationType
Journal Article, Comparative Study, Research Support, U.S. Gov't, P.H.S., Research Support, Non-U.S. Gov't