pubmed-article:2908355 | rdf:type | pubmed:Citation | lld:pubmed |
pubmed-article:2908355 | lifeskim:mentions | umls-concept:C0035820 | lld:lifeskim |
pubmed-article:2908355 | lifeskim:mentions | umls-concept:C0242957 | lld:lifeskim |
pubmed-article:2908355 | lifeskim:mentions | umls-concept:C1821244 | lld:lifeskim |
pubmed-article:2908355 | lifeskim:mentions | umls-concept:C0040682 | lld:lifeskim |
pubmed-article:2908355 | lifeskim:mentions | umls-concept:C0029005 | lld:lifeskim |
pubmed-article:2908355 | pubmed:dateCreated | 1990-1-4 | lld:pubmed |
pubmed-article:2908355 | pubmed:abstractText | p185neu, the protein product of the neu gene, is a tyrosine kinase receptor with structural similarity to the epidermal growth factor (EGF) receptor. The cognate ligand for the p185neu receptor remains unknown. We have defined: 1) stage and tissue-specific expression patterns of the neu gene product in developing tissues; 2) p185neu phosphorylation and the regulation of p185neu tyrosine kinase activity by EGF. 3) Synergistic interactions of cellular rat p185neu and EGF receptor leading to cell transformation; 4) structural and functional differences of normal and oncogenic p185neu. These observations explain some features of how p185neu is involved in normal development and neoplastic transformation. | lld:pubmed |
pubmed-article:2908355 | pubmed:language | eng | lld:pubmed |
pubmed-article:2908355 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:2908355 | pubmed:citationSubset | IM | lld:pubmed |
pubmed-article:2908355 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:2908355 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:2908355 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:2908355 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:2908355 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:2908355 | pubmed:status | MEDLINE | lld:pubmed |
pubmed-article:2908355 | pubmed:author | pubmed-author:CohenJJ | lld:pubmed |
pubmed-article:2908355 | pubmed:author | pubmed-author:WadaTT | lld:pubmed |
pubmed-article:2908355 | pubmed:author | pubmed-author:GreeneM IMI | lld:pubmed |
pubmed-article:2908355 | pubmed:author | pubmed-author:WeinerD BDB | lld:pubmed |
pubmed-article:2908355 | pubmed:author | pubmed-author:HamuroJJ | lld:pubmed |
pubmed-article:2908355 | pubmed:author | pubmed-author:DobashiKK | lld:pubmed |
pubmed-article:2908355 | pubmed:author | pubmed-author:MyersJ NJN | lld:pubmed |
pubmed-article:2908355 | pubmed:author | pubmed-author:KokalDD | lld:pubmed |
pubmed-article:2908355 | pubmed:author | pubmed-author:BrownV IVI | lld:pubmed |
pubmed-article:2908355 | pubmed:volume | 19 | lld:pubmed |
pubmed-article:2908355 | pubmed:owner | NLM | lld:pubmed |
pubmed-article:2908355 | pubmed:authorsComplete | Y | lld:pubmed |
pubmed-article:2908355 | pubmed:pagination | 45-57 | lld:pubmed |
pubmed-article:2908355 | pubmed:dateRevised | 2009-11-19 | lld:pubmed |
pubmed-article:2908355 | pubmed:meshHeading | pubmed-meshheading:2908355-... | lld:pubmed |
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pubmed-article:2908355 | pubmed:year | 1988 | lld:pubmed |
pubmed-article:2908355 | pubmed:articleTitle | The role of the neu oncogene product in cell transformation and normal development. | lld:pubmed |
pubmed-article:2908355 | pubmed:affiliation | Department of Pathology and Laboratory Medicine, University of Pennsylvania, Philadelphia 19104-6082. | lld:pubmed |
pubmed-article:2908355 | pubmed:publicationType | Journal Article | lld:pubmed |
pubmed-article:2908355 | pubmed:publicationType | Review | lld:pubmed |