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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
1208
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pubmed:dateCreated |
1989-6-16
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pubmed:abstractText |
The sex-determining region of the human Y chromosome contains a gene, ZFY, that encodes a zinc-finger protein. ZFY may prove to be the testis-determining factor. There is a closely related gene, ZFX, on the human X chromosome. In most species of placental mammals, we detect two ZFY-related loci: one on the Y chromosome and one on the X chromosome. However, there are four ZFY-homologous loci in mouse: Zfy-1 and Zfy-2 map to the sex-determining region of the mouse Y chromosome, Zfx is on the mouse X chromosome, and a fourth locus is autosomal.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:status |
MEDLINE
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pubmed:month |
Dec
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pubmed:issn |
0962-8436
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:day |
1
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pubmed:volume |
322
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
155-7
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pubmed:dateRevised |
2010-11-18
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pubmed:meshHeading |
pubmed-meshheading:2907799-Animals,
pubmed-meshheading:2907799-Chromosome Mapping,
pubmed-meshheading:2907799-Chromosomes, Human,
pubmed-meshheading:2907799-Female,
pubmed-meshheading:2907799-Genes,
pubmed-meshheading:2907799-Humans,
pubmed-meshheading:2907799-Male,
pubmed-meshheading:2907799-Recombination, Genetic,
pubmed-meshheading:2907799-Sex Determination Analysis,
pubmed-meshheading:2907799-X Chromosome,
pubmed-meshheading:2907799-Y Chromosome
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pubmed:year |
1988
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pubmed:articleTitle |
Is ZFY the sex-determining gene on the human Y chromosome?
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pubmed:affiliation |
Whitehead Institute for Biomedical Research, Nine Cambridge Center, Massachusetts 02142.
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pubmed:publicationType |
Journal Article
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