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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
5
|
| pubmed:dateCreated |
1989-3-17
|
| pubmed:abstractText |
1. Modafinil, a putative central alpha 1 adrenergic agonist, was tested in idiopathic hypersomnia and narcolepsy. 2. Sleep attacks and drowsiness were significantly decreased in 83% of 18 hypersomniac subjects and 71% of 24 narcoleptics. 3. When cataplectic episodes were not totally suppressed the association of a low dose of Clomipramine was successful in improving them. 4. Modafinil, used for at least 3 years in some patients, produces, in most cases, no peripheric sides effects, does not disturb night sleep and is never responsible of tolerance of drug dependence.
|
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:chemical | |
| pubmed:status |
MEDLINE
|
| pubmed:issn |
0278-5846
|
| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:volume |
12
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
695-700
|
| pubmed:dateRevised |
2004-11-17
|
| pubmed:meshHeading |
pubmed-meshheading:2906157-Adrenergic alpha-Agonists,
pubmed-meshheading:2906157-Adult,
pubmed-meshheading:2906157-Benzhydryl Compounds,
pubmed-meshheading:2906157-Disorders of Excessive Somnolence,
pubmed-meshheading:2906157-Female,
pubmed-meshheading:2906157-Humans,
pubmed-meshheading:2906157-Male,
pubmed-meshheading:2906157-Middle Aged,
pubmed-meshheading:2906157-Narcolepsy,
pubmed-meshheading:2906157-Sleep,
pubmed-meshheading:2906157-Sleep Disorders
|
| pubmed:year |
1988
|
| pubmed:articleTitle |
Successful treatment of idiopathic hypersomnia and narcolepsy with modafinil.
|
| pubmed:affiliation |
Lab. Neurophysiologie Clinique, Hôpital Neurologique, Lyon, France.
|
| pubmed:publicationType |
Journal Article
|