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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
1
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pubmed:dateCreated |
1988-12-20
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pubmed:abstractText |
Celiprolol (5%) was compared to timolol (0.5%) and placebo in patients with primary open angle glaucoma or ocular hypertension. A total of 28 patients participated in this double blind study and received treatment for two weeks. Intraocular pressure decreased an average of 4.4 mmHg with celiprolol and 7.1 mmHg with timolol two hours after instillation. This was maintained 12 hours after administration of timolol but not after celiprolol. There was a small but statistically significant decrease in pulse rate 2 hours after administration of timolol (from 72 to 64 beats per minute) which was not observed after celiprolol. Side effects were mild and similar for all 3 groups.
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pubmed:grant | |
pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:issn |
8756-3320
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
3
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
5-10
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pubmed:dateRevised |
2007-11-15
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pubmed:meshHeading |
pubmed-meshheading:2903202-Adrenergic beta-Antagonists,
pubmed-meshheading:2903202-Celiprolol,
pubmed-meshheading:2903202-Clinical Trials as Topic,
pubmed-meshheading:2903202-Double-Blind Method,
pubmed-meshheading:2903202-Female,
pubmed-meshheading:2903202-Glaucoma, Open-Angle,
pubmed-meshheading:2903202-Humans,
pubmed-meshheading:2903202-Intraocular Pressure,
pubmed-meshheading:2903202-Male,
pubmed-meshheading:2903202-Ocular Hypertension,
pubmed-meshheading:2903202-Propanolamines,
pubmed-meshheading:2903202-Pulse,
pubmed-meshheading:2903202-Random Allocation,
pubmed-meshheading:2903202-Timolol
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pubmed:year |
1987
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pubmed:articleTitle |
Celiprolol versus timolol and placebo: a two week double-blind comparison.
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pubmed:affiliation |
Department of Ophthalmology and Visual Science, Yale University School of Medicine, New Haven, Connecticut.
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pubmed:publicationType |
Journal Article,
Clinical Trial,
Comparative Study,
Research Support, U.S. Gov't, P.H.S.,
Randomized Controlled Trial
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