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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
1
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pubmed:dateCreated |
1988-11-8
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pubmed:abstractText |
Lymphocyte subsets were studied in forty-nine patients with SLE using monoclonal antibodies and flow cytometry. A decrease in T4+ reactive cells (helper/inducer) was the most frequent observation. Decreased T4/T8 ratios were seen in patients with increasing clinically active disease, patients with positive anti-DS-DNA, positive anti-RNP antibodies and patients with low CH50 activity. However, low T4/T8 ratios were seen in patients with negative anti-Sm. Low T4/T8 ratios were also observed in patients taking prednisone at more than 10 mg/day and in patients treated with immunosuppressive drugs.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Jun
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pubmed:issn |
0125-877X
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
6
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
23-8
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pubmed:dateRevised |
2004-11-17
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pubmed:meshHeading |
pubmed-meshheading:2901842-Adolescent,
pubmed-meshheading:2901842-Adult,
pubmed-meshheading:2901842-CD4-Positive T-Lymphocytes,
pubmed-meshheading:2901842-Female,
pubmed-meshheading:2901842-Humans,
pubmed-meshheading:2901842-Immunosuppressive Agents,
pubmed-meshheading:2901842-Lupus Erythematosus, Systemic,
pubmed-meshheading:2901842-Male,
pubmed-meshheading:2901842-Middle Aged,
pubmed-meshheading:2901842-Prednisone,
pubmed-meshheading:2901842-T-Lymphocytes
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pubmed:year |
1988
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pubmed:articleTitle |
Lymphocyte subset T4/T8 ratio in systemic lupus erythematosus: correlation with disease activity, laboratory abnormalities and treatment.
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pubmed:affiliation |
Department of Medicine, University of Mississippi Medical Center, Jackson.
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pubmed:publicationType |
Journal Article
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