Linked Life Data

2901269

Source:http://linkedlifedata.com/resource/pubmed/id/2901269

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
3 Pt 3
pubmed:dateCreated
1988-10-19
pubmed:abstractText
The inbred S/JR rat is characterized by a genetic predisposition to NaCl-induced hypertension. Although mature S/JR but not R/JR rats develop hypertension when fed a high NaCl-containing diet, this effect has not been examined during early neonatal development. S/JR and R/JR dams were maintained on 0.15% (w/w) or 8% (w/w) NaCl diets throughout gestation and lactation. Measurements of mean abdominal aortic blood pressure (MAP) were obtained in anesthetized offspring at 5, 15, and 25 days of age. This was greater in neonatal S/JR rats than R/JR rats at 5, 15, and 25 days of age. A hypertensinogenic effect of 8% NaCl was seen in R/JR at 5 and 15 days. The results indicate that the ontogeny of MAP can be influenced by pre- and postnatal dietary NaCl. More importantly, elevated MAP in the S/JR strain is a distinguishing characteristic evident throughout the neonatal period of development.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Jul
pubmed:issn
0895-7061
pubmed:author
pubmed:issnType
Print
pubmed:volume
1
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
41S-44S
pubmed:dateRevised
2009-2-24
pubmed:meshHeading
pubmed:year
1988
pubmed:articleTitle
Ontogeny of blood pressure in the inbred Dahl hypertension-sensitive and -resistant rat.
pubmed:affiliation
Department of Pediatrics, School of Medicine, State University of New York, Stony Brook 11794.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't