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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
4
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pubmed:dateCreated |
1988-6-2
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pubmed:abstractText |
Thymocytes binding in vitro to phagocytic cells of the thymic reticulum (P-TR), termed 'rosetting thymocytes', were injected intravenously into irradiated congenic mice and their migration patterns were compared with those that do not bind to P-TR, called 'non-rosetting thymocytes', similarly transferred. Donor cells, C57BL/Ka Thy 1.2, were distinguished from recipient cells, C57BL/Ka Thy 1.1 by a direct immunofluorescence technique using an anti-Thy 1.2 monoclonal antibody. The results demonstrate that the rosetting thymocytes have a greater capacity for homing back to the thymus and for populating the mesenteric lymph node and the spleen. Intrathymic transfer assay revealed that the donor-derived cells detected in the peripheral organs were of thymic origin.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
|
pubmed:month |
Apr
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pubmed:issn |
0300-9475
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
27
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
433-8
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:2896384-Animals,
pubmed-meshheading:2896384-Antigens, Surface,
pubmed-meshheading:2896384-Antigens, Thy-1,
pubmed-meshheading:2896384-Cell Differentiation,
pubmed-meshheading:2896384-Cell Movement,
pubmed-meshheading:2896384-Lymph Nodes,
pubmed-meshheading:2896384-Lymphocytes,
pubmed-meshheading:2896384-Mice,
pubmed-meshheading:2896384-Phagocytes,
pubmed-meshheading:2896384-Rosette Formation,
pubmed-meshheading:2896384-Spleen,
pubmed-meshheading:2896384-Thymus Gland
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pubmed:year |
1988
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pubmed:articleTitle |
Repopulation potential of thymocytes forming rosettes with phagocytic cells of the thymic reticulum.
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pubmed:affiliation |
INSERM U 25, CNRS LA 122, Hôpital Necker, Paris, France.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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