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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
10
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pubmed:dateCreated |
1988-1-6
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pubmed:abstractText |
The possible role of different peptidergic systems in the postictal stage of human epilepsy was studied by measuring beta-endorphin, somatostatin, and prolactin levels by radioimmunoassay of cerebrospinal fluid (CSF) from nine epileptic patients. The first sample was taken within 2 hours after generalised tonic-clonic convulsion, and the second sample was obtained interictally after 1-4 days without any kind of clinically observable seizures. beta-endorphin was elevated postictally (p = 0.044) compared with interictal levels. SLI and PROL were similar in both samples. The present study suggests that in humans beta-endorphin is released into CSF during generalised seizures. This may indicate that neurons containing beta-endorphin are activated during a seizure.
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pubmed:commentsCorrections |
http://linkedlifedata.com/resource/pubmed/commentcorrection/2890716-190556,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2890716-19969782,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2890716-283426,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2890716-2868784,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2890716-2882440,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2890716-2950209,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2890716-3965999,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2890716-3974416,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2890716-6116516,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2890716-6134222,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2890716-6140981,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2890716-6142929,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2890716-6692795,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2890716-687991,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2890716-6984318
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Oct
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pubmed:issn |
0022-3050
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
50
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1294-7
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pubmed:dateRevised |
2010-9-9
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pubmed:meshHeading |
pubmed-meshheading:2890716-Adult,
pubmed-meshheading:2890716-Epilepsy,
pubmed-meshheading:2890716-Epilepsy, Temporal Lobe,
pubmed-meshheading:2890716-Female,
pubmed-meshheading:2890716-Humans,
pubmed-meshheading:2890716-Male,
pubmed-meshheading:2890716-Middle Aged,
pubmed-meshheading:2890716-Prolactin,
pubmed-meshheading:2890716-Somatostatin,
pubmed-meshheading:2890716-beta-Endorphin
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pubmed:year |
1987
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pubmed:articleTitle |
Beta-endorphin, somatostatin, and prolactin levels in cerebrospinal fluid of epileptic patients after generalised convulsion.
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pubmed:affiliation |
Department of Neurology, University of Kuopio, Finland.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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