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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
4
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pubmed:dateCreated |
1987-1-13
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pubmed:abstractText |
The effects of several doses of MIF-1 and Tyr-MIF-1 (0.2, 0.5, 1.0 and 5.0 mg/kg, SC) on the stereotypic behavior induced by various doses (0.08, 0.2, 0.5, 1.0 and 2.0 mg/kg, SC) of apomorphine (APO) were tested in rats. MIF-1 increased the stereotypic behavior induced by 0.5 and 1.0 mg/kg of APO, but decreased the stereotypic behavior induced by 2.0 mg/kg of APO. Tyr-MIF-1 showed a biphasic effect similar to that exerted by MIF-1. The results suggest that the type of response to MIF-1 and Tyr-MIF-1 after APO is influenced by the activity of central dopaminergic neurons.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Oct
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pubmed:issn |
0091-3057
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
25
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
757-61
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:2878442-Animals,
pubmed-meshheading:2878442-Apomorphine,
pubmed-meshheading:2878442-Dose-Response Relationship, Drug,
pubmed-meshheading:2878442-Drug Interactions,
pubmed-meshheading:2878442-MSH Release-Inhibiting Hormone,
pubmed-meshheading:2878442-Male,
pubmed-meshheading:2878442-Rats,
pubmed-meshheading:2878442-Stereotyped Behavior
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pubmed:year |
1986
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pubmed:articleTitle |
Biphasic effects of MIF-1 and Tyr-MIF-1 on apomorphine-induced stereotypy in rats.
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, Non-P.H.S.
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