Linked Life Data

2867063

Source:http://linkedlifedata.com/resource/pubmed/id/2867063

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1
pubmed:dateCreated
1986-2-20
pubmed:abstractText
Two morphologically distinct types of polarization and locomotion are found in Walker carcinosarcoma cells. Spontaneously polarized cells are characterized by formation of ruffles and spikes, cells polarized in the presence of microtubule-disassembling drugs by blebbing at the leading edge. Polarization and locomotion are closely correlated. Both can be stimulated by the microtubule-disassembling agents colchicine, nocodazole and vinblastine and suppressed by taxol or cytochalasin B. The results suggest that both microfilaments and microtubules may be involved in regulating polarization and chemokinesis, and that shape changes elicited by microtubule-disassembling agents depend on microfilaments.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0251-1789
pubmed:author
pubmed:issnType
Print
pubmed:volume
6
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
33-43
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1986
pubmed:articleTitle
Shape changes and chemokinesis of Walker 256 carcinosarcoma cells in response to colchicine, vinblastine, nocodazole and taxol.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't