Linked Life Data

2865618

Source:http://linkedlifedata.com/resource/pubmed/id/2865618

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
8465
pubmed:dateCreated
1985-12-18
pubmed:abstractText
Eight patients undergoing abdominal surgery received epidural analgesia with 0.5% plain bupivacaine at a fixed dose rate (8 ml/h) for postoperative pain relief. Mean sensory level of analgesia (pin prick) was assessed hourly and regressed from a mean preoperative level of T3.7 (+/- 0.3 SEM) to T10 (+/- 0.7) at an average of 8.9 +/- 1.4 h post skin incision (range 4-16 h). Simultaneously, pain scores (4-point scale) increased from zero to 2.1 +/- 0.2. When analgesia regressed greater than or equal to 5 segments, administration of 10 mg morphine intravenously led to a pronounced cephalad increase in sensory analgesia; the initial level of analgesia was achieved in every case despite unchanged bupivacaine infusion. Simultaneously, pain score decreased to 0.3 +/- 0.3. This synergistic effect of systemic morphine on the extent of neural blockade with epidural bupivacaine may have an important role in improving postoperative pain relief.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
AIM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Nov
pubmed:issn
0140-6736
pubmed:author
pubmed:issnType
Print
pubmed:day
23
pubmed:volume
2
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
1156-7
pubmed:dateRevised
2004-11-17
pubmed:meshHeading
pubmed:year
1985
pubmed:articleTitle
Systemic morphine enhances spread of sensory analgesia during postoperative epidural bupivacaine infusion.
pubmed:publicationType
Journal Article