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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
2-3
|
pubmed:dateCreated |
1989-2-13
|
pubmed:abstractText |
The function of DnaA protein as a replisome organizer in the initiation of DNA replication is reviewed. A model is presented showing the construction of two basic types of DnaA-dependent replication origin. New data demonstrate that the dnaA box-DnaA protein complex is a transcription terminator. Only one orientation of the dnaA box results in termination of transcription. Mutation of the dnaA box within the dnaA reading frame shows that DnaA-mediated transcription termination has a role in the autoregulation of the dnaA gene.
|
pubmed:language |
eng
|
pubmed:journal | |
pubmed:citationSubset |
IM
|
pubmed:chemical | |
pubmed:status |
MEDLINE
|
pubmed:month |
Dec
|
pubmed:issn |
0006-3002
|
pubmed:author | |
pubmed:issnType |
Print
|
pubmed:day |
20
|
pubmed:volume |
951
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
351-8
|
pubmed:dateRevised |
2006-11-15
|
pubmed:meshHeading |
pubmed-meshheading:2850012-Amino Acid Sequence,
pubmed-meshheading:2850012-Bacterial Proteins,
pubmed-meshheading:2850012-Base Sequence,
pubmed-meshheading:2850012-DNA Replication,
pubmed-meshheading:2850012-Escherichia coli,
pubmed-meshheading:2850012-Molecular Sequence Data,
pubmed-meshheading:2850012-Repressor Proteins,
pubmed-meshheading:2850012-Transcription, Genetic,
pubmed-meshheading:2850012-Transcription Factors
|
pubmed:year |
1988
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pubmed:articleTitle |
Functions of the DnaA protein of Escherichia coli in replication and transcription.
|
pubmed:affiliation |
Max-Planck-Institut für molekulare Genetik, Berlin, F.R.G.
|
pubmed:publicationType |
Journal Article,
Review,
Research Support, Non-U.S. Gov't
|