Linked Life Data

2835469

Source:http://linkedlifedata.com/resource/pubmed/id/2835469

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2
pubmed:dateCreated
1988-6-16
pubmed:abstractText
An assay was developed for the detection of cytomegalovirus (CMV) antigens in blood leukocytes and evaluated for its diagnostic significance in six heart transplant recipients. Slides of cytocentrifuged blood leukocytes were prepared at regular intervals during the posttransplantation period and stained with CMV-specific monoclonal antibodies, a procedure that took 3 hours. CMV-antigen-positive leukocytes were detected in all five patients with active CMV infection but not in the patient without CMV infection. These CMV-antigen-positive cells were transiently present and first detected 10 to 28 days before there was a significant increase in serum antibody levels. It is concluded that detection of CMV antigens in blood cells is a useful assay for the early diagnosis of active CMV infection in heart transplant recipients.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0887-2570
pubmed:author
pubmed:issnType
Print
pubmed:volume
7
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
106-9
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:articleTitle
Antigen test for early diagnosis of active cytomegalovirus infection in heart transplant recipients.
pubmed:affiliation
Department of Clinical Immunology, University Hospital Groningen, The Netherlands.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't