Linked Life Data

2830411

Source:http://linkedlifedata.com/resource/pubmed/id/2830411

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
3
pubmed:dateCreated
1988-3-28
pubmed:abstractText
The quantitatively most important noradrenergic cell group of the brain is the locus coeruleus. Significantly increased cAMP concentration could be measured in spontaneously hypertensive rats in comparison to normotensive Wistar-Kyoto control rats at every stage investigated. Furthermore, both the basal activity and maximal stimulation of Ca++- and GTP-dependent adenylate cyclase as well as phosphodiesterase activity were significantly decreased in the spontaneously hypertensive rats at 14 weeks of age. The possible role of the locus coeruleus in spontaneous hypertension is presumed in counterregulatory mechanisms against rising blood pressure.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0360-4012
pubmed:author
pubmed:issnType
Print
pubmed:volume
18
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
473-8
pubmed:dateRevised
2007-11-15
pubmed:meshHeading
pubmed:year
1987
pubmed:articleTitle
Alterations in the adenylate cyclase-cAMP-phosphodiesterase system in the locus coeruleus during the development of spontaneous hypertension of the rat.
pubmed:affiliation
Department of Nephrology, University of Würzburg, Federal Republic of Germany.
pubmed:publicationType
Journal Article, Comparative Study, Research Support, Non-U.S. Gov't