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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
3
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pubmed:dateCreated |
1988-3-23
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pubmed:abstractText |
Thirty-five patients received 42 liver homografts between February 1984 and August 1985. One or more infections developed in 23 patients (66%) some time after transplantation. An average of 2.5 infections per infected patient occurred. Of 37 bacterial infections, two thirds were either bacteremias or localized intra-abdominal infections. The median onset was 29 days after operation. Thirteen viral infections were identified, with a median onset of 18 days after operation. Nine fungal infections, six disseminated and three localized, were identified, with a median onset of nine days after operation. Infection was the primary cause of death in five (14%) of 35 patients. Fatal infections were evenly distributed among bacterial (two), fungal (three), and viral (two) pathogens. Despite advances in surgical techniques and the use of cyclosporine, infection after orthotopic liver transplantation is a serious problem. Certain patients can be identified as high risks for infection and require an aggressive diagnostic workup followed by early institution of antimicrobial therapy.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
AIM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Mar
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pubmed:issn |
0004-0010
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
123
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
360-4
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pubmed:dateRevised |
2004-11-17
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pubmed:meshHeading |
pubmed-meshheading:2829792-Adolescent,
pubmed-meshheading:2829792-Adult,
pubmed-meshheading:2829792-Anti-Bacterial Agents,
pubmed-meshheading:2829792-Bacterial Infections,
pubmed-meshheading:2829792-Candidiasis,
pubmed-meshheading:2829792-Child,
pubmed-meshheading:2829792-Child, Preschool,
pubmed-meshheading:2829792-Cytomegalovirus Infections,
pubmed-meshheading:2829792-Gram-Negative Bacteria,
pubmed-meshheading:2829792-Humans,
pubmed-meshheading:2829792-Infant,
pubmed-meshheading:2829792-Infection,
pubmed-meshheading:2829792-Infection Control,
pubmed-meshheading:2829792-Liver Transplantation,
pubmed-meshheading:2829792-Middle Aged,
pubmed-meshheading:2829792-Postoperative Complications,
pubmed-meshheading:2829792-Risk Factors,
pubmed-meshheading:2829792-Virus Diseases
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pubmed:year |
1988
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pubmed:articleTitle |
Infectious complications in liver transplantation.
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pubmed:affiliation |
Department of Surgery, UCLA-Center for the Health Sciences 90024.
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pubmed:publicationType |
Journal Article
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