Linked Life Data

2826899

Source:http://linkedlifedata.com/resource/pubmed/id/2826899

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
4-6
pubmed:dateCreated
1988-2-25
pubmed:abstractText
A brief account of our present knowledge on the enterohepatic metabolism of estrogens and on the origin, metabolism and biological effects of mammalian lignans and phytoestrogens is undertaken. Furthermore, recently published results on the effects of dietary fiber, fat and carbohydrates on estrogen metabolism are reviewed. New preliminary results are presented on quantitative assays of lignans and phytoestrogens in urine of women belonging to various dietary and population groups and in a group of chimpanzees. The highest values of lignans and phytoestrogens were found in the non-human primates, and in macrobiotic, lactovegetarian and Japanese women, all groups considered having a low risk for the development of breast and other hormone-dependent cancer. New results on correlations between intake of various fibers, lignan and phytoestrogen excretion and plasma levels of estrogens, free testosterone and SHBG in women are presented. There is a significant positive correlation between the intake of fiber and urinary excretion of lignans and phytoestrogens, and the concentration of plasma SHBG. Fiber intake and urinary excretion of lignans and equol correlated negatively with plasma percentage free estradiol. Enterolactone excretion correlated negatively with plasma free testosterone. It is concluded that dietary macro- and micronutrients seem to play an important role in estrogen metabolism.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0022-4731
pubmed:author
pubmed:issnType
Print
pubmed:volume
27
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
1135-44
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed-meshheading:2826899-Animals, pubmed-meshheading:2826899-Bile, pubmed-meshheading:2826899-Breast Neoplasms, pubmed-meshheading:2826899-Diet, pubmed-meshheading:2826899-Dietary Carbohydrates, pubmed-meshheading:2826899-Dietary Fats, pubmed-meshheading:2826899-Dietary Fiber, pubmed-meshheading:2826899-Dietary Proteins, pubmed-meshheading:2826899-Enterohepatic Circulation, pubmed-meshheading:2826899-Estrogens, pubmed-meshheading:2826899-Estrogens, Non-Steroidal, pubmed-meshheading:2826899-Humans, pubmed-meshheading:2826899-Intestines, pubmed-meshheading:2826899-Isoflavones, pubmed-meshheading:2826899-Lignans, pubmed-meshheading:2826899-Liver, pubmed-meshheading:2826899-Phytoestrogens, pubmed-meshheading:2826899-Plant Extracts, pubmed-meshheading:2826899-Plant Preparations, pubmed-meshheading:2826899-Sex Hormone-Binding Globulin
pubmed:year
1987
pubmed:articleTitle
Effect of dietary components, including lignans and phytoestrogens, on enterohepatic circulation and liver metabolism of estrogens and on sex hormone binding globulin (SHBG).
pubmed:affiliation
Department of Clinical Chemistry, University of Helsinki, Meilahti Hospital, Finland.
pubmed:publicationType
Journal Article, Review, Research Support, Non-U.S. Gov't