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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
1
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pubmed:dateCreated |
1988-1-21
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pubmed:abstractText |
Mice inoculated with an artificially constructed retrovirus carrying the middle T gene of polyomavirus develop acute myeloproliferative disease with severe thrombotic and hemorrhagic disorder and impaired platelet function. The megakaryocytic lineage appears to be a target for polyoma-murine leukemia virus infection and middle T gene expression. This newly described disease represents a unique model system for studying disorders of the megakaryocytic lineage.
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pubmed:commentsCorrections |
http://linkedlifedata.com/resource/pubmed/commentcorrection/2824855-1054537,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2824855-163329,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2824855-198783,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2824855-2999420,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2824855-3083894,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2824855-3873013,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2824855-3917313,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2824855-6159641,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2824855-6170367,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2824855-6325917,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2824855-6327264,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2824855-6328036,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2824855-7055638,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2824855-7068764
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Jan
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pubmed:issn |
0022-538X
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
62
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
361-5
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pubmed:dateRevised |
2009-11-18
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pubmed:meshHeading |
pubmed-meshheading:2824855-Adenosine Triphosphate,
pubmed-meshheading:2824855-Animals,
pubmed-meshheading:2824855-Antigens, Viral, Tumor,
pubmed-meshheading:2824855-Calcimycin,
pubmed-meshheading:2824855-DNA, Recombinant,
pubmed-meshheading:2824855-Leukemia Virus, Murine,
pubmed-meshheading:2824855-Mice,
pubmed-meshheading:2824855-Myeloproliferative Disorders,
pubmed-meshheading:2824855-Platelet Aggregation,
pubmed-meshheading:2824855-Polyomavirus,
pubmed-meshheading:2824855-Thrombocythemia, Essential
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pubmed:year |
1988
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pubmed:articleTitle |
A retrovirus carrying the polyomavirus middle T gene induces acute thrombocythemic myeloproliferative disease in mice.
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pubmed:affiliation |
Centro di Endocrinologia e Oncologia Sperimentale, Consiglio Nazionale delle Ricerche, Naples, Italy.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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