| pubmed-article:2821176 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:2821176 | lifeskim:mentions | umls-concept:C0205725 | lld:lifeskim |
| pubmed-article:2821176 | lifeskim:mentions | umls-concept:C0003320 | lld:lifeskim |
| pubmed-article:2821176 | lifeskim:mentions | umls-concept:C0020966 | lld:lifeskim |
| pubmed-article:2821176 | lifeskim:mentions | umls-concept:C1305923 | lld:lifeskim |
| pubmed-article:2821176 | lifeskim:mentions | umls-concept:C0936012 | lld:lifeskim |
| pubmed-article:2821176 | lifeskim:mentions | umls-concept:C1998793 | lld:lifeskim |
| pubmed-article:2821176 | pubmed:dateCreated | 1987-11-2 | lld:pubmed |
| pubmed-article:2821176 | pubmed:abstractText | An early antigen of human cytomegalovirus (HCMV) was purified from infected cells as a 72K polypeptide by immunoaffinity chromatography using a monoclonal antibody. It was located in both nucleus and cytoplasm, and was non-glycosylated and undetectable on the surface of infected cells. Known seropositive subjects had antibody against the purified protein and it elicited proliferative T cell responses in 10 of 16 subjects. Five of 14 T cell lines established in response to the purified protein were predominantly CD8+ and of these two showed major histocompatibility complex-restricted cytotoxicity against HCMV-infected cells. This provides further evidence that antigens expressed at early times may be targets for the immune response during persistent HCMV infection. | lld:pubmed |
| pubmed-article:2821176 | pubmed:language | eng | lld:pubmed |
| pubmed-article:2821176 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2821176 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:2821176 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2821176 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2821176 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2821176 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2821176 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2821176 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:2821176 | pubmed:month | Sep | lld:pubmed |
| pubmed-article:2821176 | pubmed:issn | 0022-1317 | lld:pubmed |
| pubmed-article:2821176 | pubmed:author | pubmed-author:GrahamSS | lld:pubmed |
| pubmed-article:2821176 | pubmed:author | pubmed-author:RodgersBB | lld:pubmed |
| pubmed-article:2821176 | pubmed:author | pubmed-author:BorysiewiczLL | lld:pubmed |
| pubmed-article:2821176 | pubmed:author | pubmed-author:SissonsPP | lld:pubmed |
| pubmed-article:2821176 | pubmed:author | pubmed-author:MundinJJ | lld:pubmed |
| pubmed-article:2821176 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:2821176 | pubmed:volume | 68 ( Pt 9) | lld:pubmed |
| pubmed-article:2821176 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:2821176 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:2821176 | pubmed:pagination | 2371-8 | lld:pubmed |
| pubmed-article:2821176 | pubmed:dateRevised | 2005-5-13 | lld:pubmed |
| pubmed-article:2821176 | pubmed:meshHeading | pubmed-meshheading:2821176-... | lld:pubmed |
| pubmed-article:2821176 | pubmed:meshHeading | pubmed-meshheading:2821176-... | lld:pubmed |
| pubmed-article:2821176 | pubmed:meshHeading | pubmed-meshheading:2821176-... | lld:pubmed |
| pubmed-article:2821176 | pubmed:meshHeading | pubmed-meshheading:2821176-... | lld:pubmed |
| pubmed-article:2821176 | pubmed:meshHeading | pubmed-meshheading:2821176-... | lld:pubmed |
| pubmed-article:2821176 | pubmed:meshHeading | pubmed-meshheading:2821176-... | lld:pubmed |
| pubmed-article:2821176 | pubmed:meshHeading | pubmed-meshheading:2821176-... | lld:pubmed |
| pubmed-article:2821176 | pubmed:meshHeading | pubmed-meshheading:2821176-... | lld:pubmed |
| pubmed-article:2821176 | pubmed:meshHeading | pubmed-meshheading:2821176-... | lld:pubmed |
| pubmed-article:2821176 | pubmed:meshHeading | pubmed-meshheading:2821176-... | lld:pubmed |
| pubmed-article:2821176 | pubmed:meshHeading | pubmed-meshheading:2821176-... | lld:pubmed |
| pubmed-article:2821176 | pubmed:meshHeading | pubmed-meshheading:2821176-... | lld:pubmed |
| pubmed-article:2821176 | pubmed:year | 1987 | lld:pubmed |
| pubmed-article:2821176 | pubmed:articleTitle | Immunoaffinity purification of a 72K early antigen of human cytomegalovirus: analysis of humoral and cell-mediated immunity to the purified polypeptide. | lld:pubmed |
| pubmed-article:2821176 | pubmed:affiliation | Department of Medicine, Royal Postgraduate Medical School, London, U.K. | lld:pubmed |
| pubmed-article:2821176 | pubmed:publicationType | Journal Article | lld:pubmed |
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| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:2821176 | lld:pubmed |
