Linked Life Data

282076

Source:http://linkedlifedata.com/resource/pubmed/id/282076

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:dateCreated
1979-3-24
pubmed:abstractText
1. The serum concentrations of cholesterol and triglycerides were measured before and during the treatment of hypertension. Thirty-six patients were treated with hydrochlorothiazide and 29 with spironolactone. 2. Serum cholesterol increased from 214 to 227 mg/100 ml (P less than 0.005) and triglyceride did not change during treatment with hydrochlorothiazide. Serum triglyceride increased from 112 to 133 mg/100 ml (P less than 0.05) and cholesterol did not change during treatment with spironolactone. 3. Serum lipid responses to diuretics varied among patients. To identify patients susceptible to larger increases, subgroup analysis was carried out. Patients who were younger and had lower pretreatment serum cholesterol and systolic blood pressure had larger increments in cholesterol during treatment. In these subgroups coronary risk status did not improve during therapy. 4. The incidence of myocardial infarction may not be reduced so long as diuretics serve as first-line drugs in the treatment of mild hypertension.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Dec
pubmed:issn
0144-4107
pubmed:author
pubmed:issnType
Print
pubmed:volume
4
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
311s-314s
pubmed:dateRevised
2008-2-12
pubmed:meshHeading
pubmed:year
1978
pubmed:articleTitle
Raised serum lipid concentrations during diuretic treatment of hypertension: a study of predictive indexes.
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, P.H.S.