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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
3
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pubmed:dateCreated |
1987-10-16
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pubmed:abstractText |
Combined results of 21-DF (via the specific RIA method) and 17-OHP levels in plasma were used to support the evidence that some of the cases with idiopathic oligozoospermia (I.O.) are the result of 21-hydroxylase deficiency (C-21-HD). In our current tests, in four out of 19 males with I.O., elevated levels of 21-DF prior to ACTH stimulation (24.3 +/- 2.3 ng/dl) and after ACTH stimulation (81.2 +/- 5.2 ng/dl) in comparison to the controls (10.6 +/- 4.3 ng/dl and 36.9 +/- 10.1 ng/dl after ACTH) and other I.O. cases were observed. Only one out of these cases presented elevated 17-OHP levels prior and after ACTH stimulation in comparison to the controls and other I.O. cases. Measuring the 21-DF levels along with the 17-OHP in males suspected of C-21-HD, seems to aid the establishing of a correct diagnosis.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:issn |
0303-4569
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
19
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
393-7
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:2820268-17-Hydroxycorticosteroids,
pubmed-meshheading:2820268-17-alpha-Hydroxyprogesterone,
pubmed-meshheading:2820268-Adrenal Hyperplasia, Congenital,
pubmed-meshheading:2820268-Adrenocorticotropic Hormone,
pubmed-meshheading:2820268-Adult,
pubmed-meshheading:2820268-Cortodoxone,
pubmed-meshheading:2820268-Humans,
pubmed-meshheading:2820268-Hydroxyprogesterones,
pubmed-meshheading:2820268-Male,
pubmed-meshheading:2820268-Oligospermia
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pubmed:articleTitle |
21-Deoxycortisol (21-DF) and 17-hydroxyprogesterone (17-OHP) responses to adrenalcorticotropic hormone in males with idiopathic oligozoospermia.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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