Linked Life Data

2816421

Source:http://linkedlifedata.com/resource/pubmed/id/2816421

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2
pubmed:dateCreated
1989-12-6
pubmed:abstractText
The ultrastructural changes in the germinal membranes of Echinococcus granulosus cysts treated with d-hydrastine (3.75 mg/(kg.d), ig) for 20 d were studied. Cysts from d-hydrastine treated mice were shown by transmission electron microscope to have dissolution of the microtriches, disturbance of organelles in their arrangement, dilatation and disruption of microtubules, increase in size and number of lysosomes, a decrease in number of Golgi complexes and lessening in density and swelling of mitochondria. Under scanning electron microscope, many pits arising from the outer and inner surfaces of the germinal membrane were observed. It seems that d-hydrastine has a profound intracellular effect on experimental Echinococcus granulosus cysts in mice, and that it may be a promising drug for treating hydatidosis.
pubmed:language
chi
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Mar
pubmed:issn
0253-9756
pubmed:author
pubmed:issnType
Print
pubmed:volume
10
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
185-7
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1989
pubmed:articleTitle
[Effect of d-hydrastine on the ultrastructure of experimental Echinococcus granulosus cyst in mice].
pubmed:publicationType
Journal Article, English Abstract