Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1
pubmed:dateCreated
1989-11-7
pubmed:abstractText
Auditory papillae from three species of bird (pigeon, starling, and chick), and two species of European lizard (Podarcis muralis and Podarcis sicula) were examined by scanning electron microscopy. Hair bundles from all papillae showed tip links oriented along the direction of gradation in heights of the stereocilia (i.e. parallel to the hair-cell axis of bilateral symmetry, and so parallel to the excitatory-inhibitory axis for mechanotransduction). This orientation was seen irrespective of the overall orientation of the hair bundle within the papilla. The stereocilia formed columns, joined by the tip links, which ran parallel to the hair-cell axis of bilateral symmetry. The stereocilia within the same column tended to stay together, while those in different columns tended to separate during preparation. In many columns all the stereocilia tended to be a little taller, or a little shorter, than the equivalent stereocilia in adjacent columns, suggesting that all the stereocilia within one column had been affected by a common height determinant during development. In addition, links running laterally between stereocilia were seen, in a band near the base of the stereocilia. The results are consistent with the hypothesis that tip links are a universal feature of mechano-transducing acousticolateral hair cells, and that they are involved in sensory transduction. The results also support suggestions that the tip links may play a role in determining the heights of the stereocilia during development.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
Aug
pubmed:issn
0378-5955
pubmed:author
pubmed:issnType
Print
pubmed:volume
41
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
31-41
pubmed:dateRevised
2007-11-15
pubmed:meshHeading
pubmed:year
1989
pubmed:articleTitle
The organization of tip links and stereocilia on hair cells of bird and lizard basilar papillae.
pubmed:affiliation
Vision Touch and Hearing Research Centre, University of Queensland, St. Lucia, Australia.
pubmed:publicationType
Journal Article, Comparative Study, Research Support, Non-U.S. Gov't