Linked Life Data

2791216

Source:http://linkedlifedata.com/resource/pubmed/id/2791216

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1
pubmed:dateCreated
1989-11-17
pubmed:abstractText
Capillary lumenal narrowing in hemorrhagic shock was investigated using intravital microscopy to visualize capillaries directly in the rabbit tenuissimus muscle after a rapid single-withdrawal of 40% of the blood volume. The ensuing 1 hr shock period in the animals was marked by a protracted systemic hypotension and metabolic acidosis. Changes in capillary lumen diameter were inferred by changes in the width and length of red blood cells (RBCs) as they traversed the capillary. By the end of the shock period, RBC flux from nine experiments decreased over 60% with a -24.3 +/- 9.3% and +22.8 +/- 6.4% change in RBC width and length, respectively. The narrowed capillary lumen resulting from endothelial cell swelling elevates hydraulic resistance which may hinder resuscitation efforts to restore shock-impaired flow.
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
Sep
pubmed:issn
0092-6213
pubmed:author
pubmed:issnType
Print
pubmed:volume
29
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
27-39
pubmed:dateRevised
2007-11-15
pubmed:meshHeading
pubmed:year
1989
pubmed:articleTitle
Lumenal narrowing and endothelial cell swelling in skeletal muscle capillaries during hemorrhagic shock.
pubmed:affiliation
Pharmacia Experimental Medicine, San Diego, La Jolla 92037.
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, P.H.S.