Switch to
Predicate | Object |
---|---|
rdf:type | |
lifeskim:mentions | |
pubmed:issue |
2
|
pubmed:dateCreated |
1978-12-2
|
pubmed:abstractText |
A woman with chronic myelocytic leukemia had the Philadelphia chromosome and a complex four-break--three-chromosome rearrangement. The q32 leads to q34 portion of chromosome 9 is translocated to band q22 of chromosome 7, and at the end of this segment is attached the deleted q11 leads to qter portion of chromosome 22. A review of 12 cases of the Philadelphia chromosome originating by the rearrangement of three or more chromosomes reveals that chromosomes 9 and 22 are always involved, while the third chromosome is a different one in each case. We discuss the hypothesis that the 22q segment is always specifically attached to band 9q34 wherever this portion of 9q is transposed.
|
pubmed:language |
eng
|
pubmed:journal | |
pubmed:citationSubset |
IM
|
pubmed:status |
MEDLINE
|
pubmed:month |
Aug
|
pubmed:issn |
0340-6717
|
pubmed:author | |
pubmed:issnType |
Print
|
pubmed:day |
31
|
pubmed:volume |
43
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
133-7
|
pubmed:dateRevised |
2008-11-21
|
pubmed:meshHeading |
pubmed-meshheading:278772-Aged,
pubmed-meshheading:278772-Chromosomes, Human, 21-22 and Y,
pubmed-meshheading:278772-Chromosomes, Human, 6-12 and X,
pubmed-meshheading:278772-Female,
pubmed-meshheading:278772-Genetic Variation,
pubmed-meshheading:278772-Humans,
pubmed-meshheading:278772-Karyotyping,
pubmed-meshheading:278772-Leukemia, Myeloid,
pubmed-meshheading:278772-Translocation, Genetic
|
pubmed:year |
1978
|
pubmed:articleTitle |
Three chromosomes' (7;9;22) rearrangement and the origin of the Philadelphia chromosome.
|
pubmed:publicationType |
Journal Article,
Case Reports
|