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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
6
|
| pubmed:dateCreated |
1989-8-11
|
| pubmed:abstractText |
A retrospective study at our hospital determined the race or ethnicity of patients seen in an 8-year period who had formed antibodies to Duffy antigens. During that time, 9876 serologic investigations had been performed as a result of a positive direct or indirect antiglobulin test. Among these samples, sera from 45 previously transfused or pregnant patients contained anti-Fya and two contained anti-Fy3. Twenty-nine of the sera that contained anti-Fya (62%) were from blacks, 12 (25%) were from whites, and 6 (13%) were from Hispanics. Both examples of anti-Fy3 were made by black patients. Red cells (RBCs) from 21 of the black patients were Fy(a-b-), those from 7 were Fy(a-b+), and those from 1 could not be phenotyped. RBCs from 17 of the non-black patients were Fy(a-b+) and those from 1 could not be phenotyped. The population of transfused patients evaluated in this study was 47 percent black, 29 percent white, and 24 percent Hispanic. Calculations based on an expected Fy(a-) frequency of 88 percent in blacks, 33 percent in whites, and 20 percent in Hispanics predict that the racial makeup of the Fy(a-) population at our hospital would be 73 percent black, 18 percent white, and 9 percent Hispanic, which is not significantly different (p = 0.25) from the racial makeup of the patients forming anti-Fya and -Fy3. These data indicate that blacks make antibodies to Duffy antigens as frequently as non-blacks.
|
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:chemical | |
| pubmed:status |
MEDLINE
|
| pubmed:issn |
0041-1132
|
| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:volume |
29
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
505-7
|
| pubmed:dateRevised |
2004-11-17
|
| pubmed:meshHeading |
pubmed-meshheading:2787551-African Continental Ancestry Group,
pubmed-meshheading:2787551-Blood Group Antigens,
pubmed-meshheading:2787551-Blood Grouping and Crossmatching,
pubmed-meshheading:2787551-Blood Transfusion,
pubmed-meshheading:2787551-Continental Population Groups,
pubmed-meshheading:2787551-Cross-Sectional Studies,
pubmed-meshheading:2787551-Duffy Blood-Group System,
pubmed-meshheading:2787551-Erythroblastosis, Fetal,
pubmed-meshheading:2787551-European Continental Ancestry Group,
pubmed-meshheading:2787551-Female,
pubmed-meshheading:2787551-Hispanic Americans,
pubmed-meshheading:2787551-Humans,
pubmed-meshheading:2787551-Infant, Newborn,
pubmed-meshheading:2787551-Isoantibodies,
pubmed-meshheading:2787551-Male,
pubmed-meshheading:2787551-Phenotype,
pubmed-meshheading:2787551-Pregnancy,
pubmed-meshheading:2787551-Risk,
pubmed-meshheading:2787551-United States
|
| pubmed:articleTitle |
The prevalence of immunization to Duffy antigens in a population of known racial distribution.
|
| pubmed:affiliation |
Department of Medical Laboratory Sciences, University of Illinois, Chicago.
|
| pubmed:publicationType |
Journal Article
|