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Predicate | Object |
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rdf:type | |
lifeskim:mentions |
umls-concept:C0001128,
umls-concept:C0006675,
umls-concept:C0014653,
umls-concept:C0021294,
umls-concept:C0022646,
umls-concept:C0031705,
umls-concept:C0204695,
umls-concept:C0221102,
umls-concept:C0489829,
umls-concept:C0728731,
umls-concept:C0815327,
umls-concept:C1280500,
umls-concept:C1442989,
umls-concept:C1515075,
umls-concept:C1705501
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pubmed:issue |
4
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pubmed:dateCreated |
1989-10-23
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pubmed:abstractText |
In 19 preterm infants fed a standard formula for prematures (calcium (Ca) 13.5 mmol/l; phosphorus (P) 12.9 mmol/l), biochemical parameters of blood, serum and urine were determined before and during supplementation with Ca-L-lactate (final Ca concentration 20 mmol/l). In 8 preterm boys Ca and P balance were evaluated in addition. During Ca supplementation, the serum Ca levels, urine pH (without supplement 6.31, with supplement 6.73), and calciuria (46 mumol/kg/d vs. 98 mumol/kg/d) were increased, and urinary P (1.05 mmol/kg/d vs. 0.65 mmol/kg/d) and net acid excretion (1.70 mEq/kg/d vs. 0.89 mEq/kg/d) were decreased. Balance studies showed increased net intestinal Ca absorption during supplementation (37% vs. 56%) as well as improved Ca (0.8 mmol/kg/d vs. 1.85 mmol/kg/d) and P retention (0.97 mmol/kg/d vs. 1.45 mmol/kg/d). These data show that increased Ca intake given to optimize the Ca:P ratio improves mineral retention in preterm infants fed a standard formula. Ca and P intake should be thoroughly balanced to avoid side-effects like hypercalciuria or high renal net acid excretion.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Jul
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pubmed:issn |
0001-656X
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
78
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
525-31
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pubmed:dateRevised |
2009-11-11
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pubmed:meshHeading |
pubmed-meshheading:2782067-Calcium,
pubmed-meshheading:2782067-Humans,
pubmed-meshheading:2782067-Infant, Newborn,
pubmed-meshheading:2782067-Infant, Premature,
pubmed-meshheading:2782067-Infant Food,
pubmed-meshheading:2782067-Intestinal Absorption,
pubmed-meshheading:2782067-Kidney,
pubmed-meshheading:2782067-Lactates,
pubmed-meshheading:2782067-Lactic Acid,
pubmed-meshheading:2782067-Male,
pubmed-meshheading:2782067-Phosphorus
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pubmed:year |
1989
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pubmed:articleTitle |
Effect of calcium supplementation on calcium and phosphorus balance and renal net acid excretion in preterm infants fed a standard formula.
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pubmed:affiliation |
Institute of Child Nutrition, Children's Hospital, Dortmund, FRG.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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