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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
3
|
pubmed:dateCreated |
1989-10-26
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pubmed:abstractText |
A 41 years old male patient suffering from angina pectoris was treated with diltiazem (Tildiem). He was administered with nifedipine (Adalate) 3 times in succession and each time either complete or partial intestinal occlusion occurred. A laparotomy was carried out after the first occlusion, but no organic lesions were found. The search for an alternate non-drug related explanation proved negative. The most likely hypothesis is that of a direct relaxant activity on intestinal smooth muscle, which would explain the functional nature of the occlusion. Therefore it must be considered that the two drugs acted synergistically.
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pubmed:language |
fre
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:issn |
0040-5957
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pubmed:author | |
pubmed:issnType |
Print
|
pubmed:volume |
44
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
|
pubmed:pagination |
201-2
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:2781505-Adult,
pubmed-meshheading:2781505-Calcium Channel Blockers,
pubmed-meshheading:2781505-Diltiazem,
pubmed-meshheading:2781505-Drug Synergism,
pubmed-meshheading:2781505-Humans,
pubmed-meshheading:2781505-Intestinal Obstruction,
pubmed-meshheading:2781505-Male,
pubmed-meshheading:2781505-Nifedipine
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pubmed:articleTitle |
[Acute intestinal occlusion and calcium antagonists].
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pubmed:publicationType |
Journal Article,
English Abstract,
Case Reports
|