Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
3
pubmed:dateCreated
1989-10-19
pubmed:abstractText
A technique based on inhalation of nebulized albumin minimicrospheres labeled with 99mTc (HAMM) was applied to visualize the redistribution of convective ventilation in the lung after a mucokinetic drug treatment. A randomized double-blind study comparing the effect of 7 days treatment with 800 mg daily oral sobrerol versus placebo in two groups of 10 patients each, affected by chronic bronchitis, was performed. Routine pulmonary function tests (PFT) and alveolar-arterial (Aa) gradients of oxygen and carbon dioxide were performed. Both PFT and Aa gradients did not show significant modification, but the inhomogeneity of HAMM deposition resulted significantly reduced after sobrerol treatment. By means of HAMM technique it was possible to show objectively the reduction of bronchial obstruction secondary to sobrerol treatment.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0392-0208
pubmed:author
pubmed:issnType
Print
pubmed:volume
33
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
258-63
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:articleTitle
Monodisperse labeled aerosol to visualize airflow redistribution in the lung after a mucokinetic drug.
pubmed:publicationType
Journal Article, Clinical Trial, Randomized Controlled Trial, Research Support, Non-U.S. Gov't