Linked Life Data

2778104

Source:http://linkedlifedata.com/resource/pubmed/id/2778104

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
4
pubmed:dateCreated
1989-10-19
pubmed:abstractText
The prenatal development of the rabbit's retinal projections to the superior colliculus (SC) was studied by using anterograde transport of horseradish peroxidase injected intraocularly. Fetuses aged embryonic day 21 (E21) to E29 and an adult rabbit were examined. Gestation in the rabbit is 30-31 days. On E21 contralaterally projecting retinal fibers invade across the entire SC. Their distribution is initially diffuse within the superficial laminae, but by E29 they have a distinct stratified appearance. Ipsilaterally projecting retinal fibers invade the rostral half of the SC on E21. By E23 they cover the entire SC and overlap the contralateral fibers both tangentially and radially. The ipsilateral fibers for the most part are sparsely distributed, but they form a dense focal distribution in the rostrolateral quarter of the SC. This focus straddles the stratum griseum superficiale/stratum opticum (SGS/SO) border. On E25 the ipsilateral fibers maintain their widespread distribution and focal rostrolateral concentration. By E27 they are excluded almost entirely from the caudal half of the SC and are reduced in density in the rostromedial quarter of the nucleus. On E29 the ipsilateral terminal field forms distinct patches and bands that are restricted to the rostrolateral quarter of the SC and are confined to the SGS/SO border. Thus, a few days before birth the pattern and location of the ipsilateral retinocollicular projection resemble those seen in the adult. The early widespread distribution of the ipsilaterally projecting retinal fibers to the SC and their eventual restriction in the fetal rabbit are consistent with the development of this projection in other mammalian orders.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Aug
pubmed:issn
0021-9967
pubmed:author
pubmed:issnType
Print
pubmed:day
22
pubmed:volume
286
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
504-13
pubmed:dateRevised
2007-11-15
pubmed:meshHeading
pubmed:year
1989
pubmed:articleTitle
Prenatal development of retinocollicular projections in the rabbit: an HRP study.
pubmed:affiliation
Department of Human Anatomy, University of Oxford, England.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't