|
rdf:type |
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lifeskim:mentions |
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pubmed:dateCreated |
1989-10-5
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pubmed:abstractText |
Venoruton offers a protection against hypoxic stress-induced neurotoxicity (convulsions and death) in mice. It also inhibits free radical generation, since it produces a concentration-dependent (5-160 micrograms/10(6) cells/ml) decrease of chemiluminescence response from human neutrophils. The maximum inhibition was observed at 140 micrograms/10(6) cells/ml. The in vivo protective effect against hypoxic stress-induced neurotoxicity has been correlated to the inhibitory action of venoruton on oxygen free radical generation.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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|
pubmed:status |
MEDLINE
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|
pubmed:issn |
0301-4533
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|
pubmed:author |
|
|
pubmed:issnType |
Print
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|
pubmed:volume |
299
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
127-33
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:2774763-Animals,
pubmed-meshheading:2774763-Anoxia,
pubmed-meshheading:2774763-Anticoagulants,
pubmed-meshheading:2774763-Dose-Response Relationship, Drug,
pubmed-meshheading:2774763-Female,
pubmed-meshheading:2774763-Free Radicals,
pubmed-meshheading:2774763-Hydroxyethylrutoside,
pubmed-meshheading:2774763-Luminescent Measurements,
pubmed-meshheading:2774763-Male,
pubmed-meshheading:2774763-Mice,
pubmed-meshheading:2774763-Nervous System Diseases,
pubmed-meshheading:2774763-Neutrophils,
pubmed-meshheading:2774763-Oxygen Consumption,
pubmed-meshheading:2774763-Rutin
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|
pubmed:articleTitle |
Effect of venoruton on hypoxic stress-induced neurotoxicity in mice and oxygen free radical generation by human neutrophils.
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pubmed:affiliation |
Department of Pharmaceutical Sciences, Panjab University, Chandigarh India.
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pubmed:publicationType |
Journal Article,
In Vitro
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