Linked Life Data

2772002

Source:http://linkedlifedata.com/resource/pubmed/id/2772002

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
4
pubmed:dateCreated
1989-9-28
pubmed:abstractText
Biodegradable polymers get more interest for the preparation of drug formulations. Their main advantage is their physiological safety. Polylactic acid is one of the biodegradable polymers. It was prepared by the direct polyesterification of lactic acid and by polymerisation of the cyclic oligomers. Both the polymers were identified by elementary analysis, by IR spectroscopy, by X-ray-test and by the molecular mass. They differ in their molecular mass and in the degree of the crystalline state. The determination of the grain size, moisture content, flowability and of the parameters for the direct compression were carried out with regard to the use of polylactic acid as auxiliary substance for the direct compression. The results show, that polylactic acid which was prepared on the basis of polyesterification, is a very suitable auxiliary substance for the direct compression.
pubmed:language
ger
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Apr
pubmed:issn
0031-7144
pubmed:author
pubmed:issnType
Print
pubmed:volume
44
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
276-9
pubmed:dateRevised
2008-11-21
pubmed:meshHeading
pubmed:year
1989
pubmed:articleTitle
[Preparation of peroral sustained release drug forms on a base of biodegradable polymers. 1. Preparation and characterization of polylactic acid].
pubmed:affiliation
Sektion Chemie, Wissenschaftsbereich Pharmazie der Humboldt-Universität zu Berlin.
pubmed:publicationType
Journal Article, English Abstract