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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
8
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pubmed:dateCreated |
1989-10-12
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pubmed:abstractText |
During an outbreak of diarrheal illness among residents of a trailer park in rural Vermont, 37 (30%) of 122 residents met the case definition of outbreak-related giardiasis. Convalescent-phase sera from 24 residents and 20 nonresident control subjects were tested by enzyme-linked immunosorbent assay for immunoglobulin G (IgG), IgM, and IgA antibodies to Giardia lamblia. Residents showed higher levels of parasite-specific antibody than did nonresident controls for IgG and IgA but not IgM. Nine residents with giardiasis had a higher median level of G. lamblia-specific IgA but not IgG or IgM than 15 healthy residents (0.61 versus 0.16 optical density units; P = 0.004). Moreover, parasite-specific IgA levels were higher in those consuming tap water than in those who did not (0.31 versus 0.08 optical density units; P = 0.03) and increased with increasing water consumption. Levels of serum antibody to G. lamblia, particularly IgA, may be useful in determining exposure to G. lamblia-contaminated water and illness from G. lamblia during waterborne outbreaks of diarrheal illness.
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pubmed:commentsCorrections |
http://linkedlifedata.com/resource/pubmed/commentcorrection/2768460-2715318,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2768460-2873438,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2768460-2886069,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2768460-3346571,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2768460-3579073,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2768460-3680997,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2768460-3782461,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2768460-3794398,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2768460-3819477,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2768460-3911906,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2768460-4045243,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2768460-622089,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2768460-7014351
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Aug
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pubmed:issn |
0095-1137
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
27
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1707-10
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pubmed:dateRevised |
2009-11-18
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pubmed:meshHeading |
pubmed-meshheading:2768460-Adult,
pubmed-meshheading:2768460-Animals,
pubmed-meshheading:2768460-Antibodies, Protozoan,
pubmed-meshheading:2768460-Disease Outbreaks,
pubmed-meshheading:2768460-Female,
pubmed-meshheading:2768460-Gastroenteritis,
pubmed-meshheading:2768460-Giardia,
pubmed-meshheading:2768460-Giardiasis,
pubmed-meshheading:2768460-Humans,
pubmed-meshheading:2768460-Immunoglobulin A,
pubmed-meshheading:2768460-Immunoglobulin G,
pubmed-meshheading:2768460-Immunoglobulin M,
pubmed-meshheading:2768460-Intestinal Diseases, Parasitic,
pubmed-meshheading:2768460-Male,
pubmed-meshheading:2768460-Middle Aged,
pubmed-meshheading:2768460-Rural Population,
pubmed-meshheading:2768460-Vermont,
pubmed-meshheading:2768460-Water Supply
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pubmed:year |
1989
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pubmed:articleTitle |
Elevated levels of immunoglobulin A to Giardia lamblia during a waterborne outbreak of gastroenteritis.
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pubmed:affiliation |
Epidemiology Division, Vermont Department of Health, Burlington 05402.
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, Non-P.H.S.
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