Linked Life Data

2765880

Source:http://linkedlifedata.com/resource/pubmed/id/2765880

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1
pubmed:dateCreated
1989-9-22
pubmed:abstractText
The objective was to determine if corticopetal basal forebrain neurons could co-synthesize different transmitters. Histochemical labeling of a molecular marker of connectivity (wheat germ agglutinin lectin-bound horseradish peroxidase [HRP]; axonal uptake and retrograde transport from neocortex) and immunohistochemical labeling of molecular markers of transmitter synthesis (glutamic acid decarboxylase [GAD]: choline acetyltransferase [ChAT]) were combined in adult cats and examined by light microscopy. Adjoining partial profiles of the same neurons in the basal forebrain co-localized GAD + HRP and ChAT + HRP in adjacent faces of serial tissue sections. GAD + ChAT were also co-localized within individual profiles of neurons in the basal forebrain from single tissue sections. The results indicate that infrequent corticopetal neurons in the basal forebrain can produce both gamma-aminobutyric acid and acetylcholine.
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Jul
pubmed:issn
0006-8993
pubmed:author
pubmed:issnType
Print
pubmed:day
3
pubmed:volume
491
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
163-8
pubmed:dateRevised
2007-11-14
pubmed:meshHeading
pubmed:year
1989
pubmed:articleTitle
Transmitter cosynthesis by corticopetal basal forebrain neurons.
pubmed:affiliation
Department of Anatomy and Cell Biology, School of Medicine, University of California, Los Angeles 90024.
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, P.H.S.