Linked Life Data

2763258

Source:http://linkedlifedata.com/resource/pubmed/id/2763258

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
6
pubmed:dateCreated
1989-9-15
pubmed:abstractText
In the adult the distributions of ventilation and of perfusion show the same directional dependence on gravity. In children, however, the distribution of ventilation in response to gravity is the reverse of that seen in adults. The aim of the current study was to determine whether perfusion showed the same reversal in children or followed the adult pattern. Distribution of perfusion was measured with intravenous technetium-99m macroaggregated albumin and distribution of ventilation with inhaled krypton-81m. Eighteen children and seven adults were studied; they had been referred for lung scanning for various respiratory problems. The effect of gravity was examined by giving aliquots of macroaggregated albumin and 81mKr by inhalation to the subject in the supine and the lateral decubitus position. Counts in the dependent lung were compared with those in the upper lung. The dependent lung in the lateral decubitus position received more of the total perfusion than it did in the supine position in seven children with a normal chest radiograph (mean 7.0%, range 4.8-10.9% more) and in 11 children with an abnormal radiograph (mean 3.4%(0.1-10.0%)). Ventilation, however, changed in the opposite direction, falling by 7.1% (-3.2% to -12.8%) in five children with a normal chest radiograph and 11.2% (-2.8% to -19.3%) in eight children with an abnormal radiograph. Fractional V/fractional Q (an index of the ventilation:perfusion ratio) decreased in the dependent lung in the children when they moved from the supine to the decubitus position. The same directional change was recorded in adults, but it was significantly less than in the children, irrespective of whether the chest radiograph was abnormal. In children and adults with various respiratory problems the effect of posture on the distribution of perfusion is similar.
pubmed:grant
pubmed:commentsCorrections
http://linkedlifedata.com/resource/pubmed/commentcorrection/2763258-1182453, http://linkedlifedata.com/resource/pubmed/commentcorrection/2763258-13442585, http://linkedlifedata.com/resource/pubmed/commentcorrection/2763258-13480946, http://linkedlifedata.com/resource/pubmed/commentcorrection/2763258-13844133, http://linkedlifedata.com/resource/pubmed/commentcorrection/2763258-13864417, http://linkedlifedata.com/resource/pubmed/commentcorrection/2763258-14085650, http://linkedlifedata.com/resource/pubmed/commentcorrection/2763258-14425845, http://linkedlifedata.com/resource/pubmed/commentcorrection/2763258-4069178, http://linkedlifedata.com/resource/pubmed/commentcorrection/2763258-4643846, http://linkedlifedata.com/resource/pubmed/commentcorrection/2763258-4862981, http://linkedlifedata.com/resource/pubmed/commentcorrection/2763258-4938395, http://linkedlifedata.com/resource/pubmed/commentcorrection/2763258-5912744, http://linkedlifedata.com/resource/pubmed/commentcorrection/2763258-5912746, http://linkedlifedata.com/resource/pubmed/commentcorrection/2763258-6406888, http://linkedlifedata.com/resource/pubmed/commentcorrection/2763258-6463424, http://linkedlifedata.com/resource/pubmed/commentcorrection/2763258-6707799, http://linkedlifedata.com/resource/pubmed/commentcorrection/2763258-7433778
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Jun
pubmed:issn
0040-6376
pubmed:author
pubmed:issnType
Print
pubmed:volume
44
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
480-4
pubmed:dateRevised
2009-11-18
pubmed:meshHeading
pubmed:year
1989
pubmed:articleTitle
Effects of posture on the distribution of pulmonary ventilation and perfusion in children and adults.
pubmed:affiliation
Department of Paediatric Radiology, Hospital for Sick Children, London.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't