Linked Life Data

2748546

Source:http://linkedlifedata.com/resource/pubmed/id/2748546

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
4
pubmed:dateCreated
1989-8-15
pubmed:abstractText
Intraperitoneal administration of an anaesthetic dose of ethanol, 3.0 mg/kg, produced rapid rhythmic jaw movements (RJM) in rats. The peak effect (90 RJM/min.) occurred after 5 min., and all movements ceased after about 15 min. Clozapine, (4.4 mg/kg intraperitoneally) completely abolished this RJM phenomenon, whereas halopridol (0.5 mg/kg intraperitoneally), apomorphine (1.0 mg/kg subcutaneously) and atropine (10 mg/kg intraperitoneally) reduced it. It is suggested that the postulated brain stem masticatory pattern generator is activated or released from inhibition during induction of ethanol anaesthesia. Apparently this masticatory movement pacemaker is amenable to pharmacological manipulation, as shown by the present experiments.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Apr
pubmed:issn
0901-9928
pubmed:author
pubmed:issnType
Print
pubmed:volume
64
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
378-9
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1989
pubmed:articleTitle
Rhythmic jaw movements induced by ethanol in rats.
pubmed:affiliation
Psychiatric Research Center, Uppsala, Sweden.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't