Linked Life Data

2740538

Source:http://linkedlifedata.com/resource/pubmed/id/2740538

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2
pubmed:dateCreated
1989-8-4
pubmed:abstractText
An experimental model of posterior spine arthrodesis in dogs was created using 3 types of calcium phosphate biomaterials already known for their applications as bone substitutes, namely: hydroxyapatite (HA), which is not readily resorbable; highly resorbable tricalcium phosphate (TCP); and a mixture of HA and TCP (BCP), the resorbability of which depends on the proportion of HA and TCP. The BCP implants had a macroporous structure, whilst the HA and TCP implants were used in dense form. The creation of macropores increases the surface exchange area, thus enabling the osseous colonization processes. By carefully removing the posterior articular facets it was possible to remove the articular surfaces and to fit into each appropriate location a block a few millimeters in diameter. The anatomopathological assessment was performed using histological methods, transmission electron microscopy, and energy dispersion microprobe analysis. Our results indicate that calcium phosphate ceramics may be used as bone substitutes for carrying out arthrodeses, provided (1) immediate immobilization using a spine containment technique is effected; (2) their chemical composition is sufficiently stable over time; (3) they are sufficiently bioactive so as to allow their colonization and replacement by bone.
pubmed:language
fre
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0035-1040
pubmed:author
pubmed:issnType
Print
pubmed:volume
75
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
65-71
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1989
pubmed:articleTitle
[Comparative study of bioactive calcium phosphate ceramics after implantation in spongy bone in dogs. Histologic, ultrastructural and electron probe microanalysis].
pubmed:affiliation
U 225 INSERM, Unité de Recherche INSERM sur les Tissus Calcifiés, UFR Odontologie, Nantes.
pubmed:publicationType
Journal Article, Comparative Study, English Abstract