Switch to
| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
6
|
| pubmed:dateCreated |
1989-6-30
|
| pubmed:abstractText |
Serum samples from 557 individuals participating in studies from four separate lowland and highland populations in Papua New Guinea exhibited consistently false-positive results for human T lymphotropic virus (HTLV) type 1 (10%) and human immunodeficiency virus (HIV) type 1 (5%) antibody in direct antiglobulin and agglutination assays. All serum samples were negative in competitive ELISAs and radioimmunoassays for HTLV-1 and HIV-1; selected samples of reactive sera were negative in an HTLV-2 competitive ELISA. Immunofluorescent antibody tests using HTLV-1 infected cells correlated poorly with ELISA results. None of the sera from Papua New Guinea neutralized vesicular stomatitis virus pseudotypes of HTLV-1. By Western blot analysis, only three serum samples were weakly reactive to HTLV-1 gag proteins. These studies suggest there is as yet no firm evidence of HTLV-1, HTLV-2, or HIV-1 infection in Papua New Guinea, although there may be a low prevalence.
|
| pubmed:grant | |
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
AIM
|
| pubmed:chemical | |
| pubmed:status |
MEDLINE
|
| pubmed:month |
Jun
|
| pubmed:issn |
0022-1899
|
| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:volume |
159
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
1025-8
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| pubmed:dateRevised |
2009-9-29
|
| pubmed:meshHeading |
pubmed-meshheading:2723452-Acquired Immunodeficiency Syndrome,
pubmed-meshheading:2723452-Adolescent,
pubmed-meshheading:2723452-Adult,
pubmed-meshheading:2723452-Agglutination Tests,
pubmed-meshheading:2723452-Binding, Competitive,
pubmed-meshheading:2723452-Child,
pubmed-meshheading:2723452-Child, Preschool,
pubmed-meshheading:2723452-Enzyme-Linked Immunosorbent Assay,
pubmed-meshheading:2723452-False Positive Reactions,
pubmed-meshheading:2723452-Female,
pubmed-meshheading:2723452-HIV Antibodies,
pubmed-meshheading:2723452-HIV-1,
pubmed-meshheading:2723452-HTLV-I Antibodies,
pubmed-meshheading:2723452-HTLV-I Infections,
pubmed-meshheading:2723452-HTLV-II Antibodies,
pubmed-meshheading:2723452-HTLV-II Infections,
pubmed-meshheading:2723452-Humans,
pubmed-meshheading:2723452-Immunoblotting,
pubmed-meshheading:2723452-Infant,
pubmed-meshheading:2723452-Male,
pubmed-meshheading:2723452-Middle Aged,
pubmed-meshheading:2723452-Papua New Guinea,
pubmed-meshheading:2723452-Radioimmunoassay,
pubmed-meshheading:2723452-Sex Factors
|
| pubmed:year |
1989
|
| pubmed:articleTitle |
HTLV-1 infection in Papua New Guinea: evidence for serologic false positivity.
|
| pubmed:affiliation |
Chester Beatty Laboratories, Department of Virology, St. Thomas's Hospital Medical School, London, UK.
|
| pubmed:publicationType |
Journal Article
|