Linked Life Data

270863

Source:http://linkedlifedata.com/resource/pubmed/id/270863

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
4
pubmed:dateCreated
1978-1-27
pubmed:abstractText
The influence on the duration of CR and survival of 2 modalities (MTX + hydrocortisone IT, with and without TCT) for the prevention of meningeal CNS involvement was assessed in 24 children with acute lymphoblastic leukemia. Of the 9 subjects who received MTX and hydrocortisone only, 42% were still in CR 33 months after its attainment, as opposed to 75% of the 15 who also received TCT. Survival at 33 months after diagnosis was 89% and 82% in the 2 groups. The results are compared with those obtained in an earlier series of 14 children who received no prophylactic treatment. Here CR at 45 months was 25% and survival 46%. Eight subjects died, as opposed to 3 (1 in CR) in the present series.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0300-8916
pubmed:author
pubmed:issnType
Print
pubmed:volume
63
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
367-72
pubmed:dateRevised
2008-12-12
pubmed:meshHeading
pubmed:articleTitle
Prevention of meningeal CNS involvement as a factor influencing the duration of complete remission and survival in childhood acute lymphoblastic leukemia.
pubmed:publicationType
Journal Article, Clinical Trial, Controlled Clinical Trial