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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
1
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pubmed:dateCreated |
1989-5-23
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pubmed:abstractText |
Fourteen patients with advanced pretreated breast cancer were treated with vindesine in continuous venous infusion (1.5 mg/sm/24 hours for 72 hours every 3 weeks). A totally implanted venous access and a portable pump were used. A total of 33 courses was administered. No objective response was observed and treatment was stopped. Drug-related toxicity consisted mainly of alopecia (64% of patients), nausea and vomiting (29%) and mucositis (29%). Catheter - related toxicity was observed in 6 patients (43%) and consisted of infection of the skin pocket in 4 patients and dislodging of the needle and catheter break in one patient. The feasibility of continuous venous infusion of vesicant drugs in outpatients is discussed.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:issn |
0250-7005
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
9
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
141-3
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pubmed:dateRevised |
2004-11-17
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pubmed:meshHeading |
pubmed-meshheading:2705743-Adult,
pubmed-meshheading:2705743-Aged,
pubmed-meshheading:2705743-Breast Neoplasms,
pubmed-meshheading:2705743-Female,
pubmed-meshheading:2705743-Humans,
pubmed-meshheading:2705743-Infusion Pumps,
pubmed-meshheading:2705743-Infusions, Intravenous,
pubmed-meshheading:2705743-Middle Aged,
pubmed-meshheading:2705743-Neoplasm Metastasis,
pubmed-meshheading:2705743-Vindesine
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pubmed:articleTitle |
Continuous venous infusion of vindesine in metastatic breast cancer: experience with a subcutaneously implanted system and portable pump.
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pubmed:affiliation |
Istituto Nazionale per la Ricerca sul Cancro, Genova, Italy.
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pubmed:publicationType |
Journal Article
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