| pubmed-article:2682643 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:2682643 | lifeskim:mentions | umls-concept:C0036025 | lld:lifeskim |
| pubmed-article:2682643 | lifeskim:mentions | umls-concept:C0008546 | lld:lifeskim |
| pubmed-article:2682643 | lifeskim:mentions | umls-concept:C0678594 | lld:lifeskim |
| pubmed-article:2682643 | pubmed:issue | 21 | lld:pubmed |
| pubmed-article:2682643 | pubmed:dateCreated | 1989-12-8 | lld:pubmed |
| pubmed-article:2682643 | pubmed:abstractText | We have developed a method for partially purifying chromatin from Saccharomyces cerevisiae (baker's yeast) to a level suitable for studies of its higher-order folding. This has required the use of yeast strains that are free of the ubiquitous yeast "killer" virus. Results from dynamic light scattering, electron microscopy, and x-ray diffraction show that the yeast chromatin undergoes a cation-dependent folding into 30-nm filaments that resemble those characteristic of higher-cell chromatin; moreover, the packing of nucleosomes within the yeast 30-nm filaments is similar to that of higher cells. These results imply that yeast has a protein or protein domain that serves the role of the histone H 1 found in higher cells; physical and genetic studies of the yeast activity could help elucidate the structure and function of H 1. Images of the yeast 30-nm filaments can be used to test crossed-linker models for 30-nm filament structure. | lld:pubmed |
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| pubmed-article:2682643 | pubmed:language | eng | lld:pubmed |
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| pubmed-article:2682643 | pubmed:citationSubset | IM | lld:pubmed |
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| pubmed-article:2682643 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:2682643 | pubmed:month | Nov | lld:pubmed |
| pubmed-article:2682643 | pubmed:issn | 0027-8424 | lld:pubmed |
| pubmed-article:2682643 | pubmed:author | pubmed-author:WidomJJ | lld:pubmed |
| pubmed-article:2682643 | pubmed:author | pubmed-author:LowaryP TPT | lld:pubmed |
| pubmed-article:2682643 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:2682643 | pubmed:volume | 86 | lld:pubmed |
| pubmed-article:2682643 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:2682643 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:2682643 | pubmed:pagination | 8266-70 | lld:pubmed |
| pubmed-article:2682643 | pubmed:dateRevised | 2009-11-18 | lld:pubmed |
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| pubmed-article:2682643 | pubmed:year | 1989 | lld:pubmed |
| pubmed-article:2682643 | pubmed:articleTitle | Higher-order structure of Saccharomyces cerevisiae chromatin. | lld:pubmed |
| pubmed-article:2682643 | pubmed:affiliation | Department of Chemistry, University of Illinois, Urbana 61801. | lld:pubmed |
| pubmed-article:2682643 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:2682643 | pubmed:publicationType | Comparative Study | lld:pubmed |
| pubmed-article:2682643 | pubmed:publicationType | Research Support, U.S. Gov't, P.H.S. | lld:pubmed |
| pubmed-article:2682643 | pubmed:publicationType | Research Support, U.S. Gov't, Non-P.H.S. | lld:pubmed |
| pubmed-article:2682643 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
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