Switch to
Predicate | Object |
---|---|
rdf:type | |
lifeskim:mentions | |
pubmed:issue |
3
|
pubmed:dateCreated |
1989-10-25
|
pubmed:abstractText |
Endothelin-1 (ET-1) is an endothelium-derived vasoconstrictor peptide with potent pressor activity. We studied the effect of ET-1 on release of arginine-vasopressin (AVP) from perifused rat hypothalamus. ET-1 (10(-10) to 10(-8) M) significantly stimulated AVP release. The ET-1-induced AVP release was completely blocked in the presence of nicardipine. Our results suggest a possible involvement of ET in the regulation of AVP release.
|
pubmed:language |
eng
|
pubmed:journal | |
pubmed:citationSubset |
IM
|
pubmed:chemical | |
pubmed:status |
MEDLINE
|
pubmed:month |
Sep
|
pubmed:issn |
0006-291X
|
pubmed:author | |
pubmed:issnType |
Print
|
pubmed:day |
29
|
pubmed:volume |
163
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
1332-7
|
pubmed:dateRevised |
2006-11-15
|
pubmed:meshHeading |
pubmed-meshheading:2675840-Animals,
pubmed-meshheading:2675840-Arginine Vasopressin,
pubmed-meshheading:2675840-Endothelins,
pubmed-meshheading:2675840-Endothelium, Vascular,
pubmed-meshheading:2675840-Hypothalamus,
pubmed-meshheading:2675840-Kinetics,
pubmed-meshheading:2675840-Male,
pubmed-meshheading:2675840-Peptides,
pubmed-meshheading:2675840-Perfusion,
pubmed-meshheading:2675840-Rats,
pubmed-meshheading:2675840-Rats, Inbred Strains
|
pubmed:year |
1989
|
pubmed:articleTitle |
Effect of endothelin-1 on release of arginine-vasopressin from perifused rat hypothalamus.
|
pubmed:affiliation |
Second Department of Internal Medicine, Tokyo Medical and Dental University, Japan.
|
pubmed:publicationType |
Journal Article,
In Vitro,
Research Support, Non-U.S. Gov't
|