Linked Life Data

2662963

Source:http://linkedlifedata.com/resource/pubmed/id/2662963

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
6
pubmed:dateCreated
1989-8-4
pubmed:abstractText
Traditionally, plant viruses are viewed as harmful, undesirable pathogens. However, their genomes can provide several useful 'designer functions' or 'sequence modules' with which to tailor future gene vectors for plant or general biotechnology. The majority (77%) of known plant viruses have single-stranded RNA of the messenger (protein coding) sense as their genetic material. Over the past 4 years, improved in vitro transcription systems and the construction of partial or full-length DNA copies of several plant RNA viruses have enhanced our ability to manipulate and study their genomes, particularly in the context of their pathogenic interactions with host plants. Recently, two forms of genetically engineered protection against plant virus infections have been reported. In both, a virus-related 'interfering' molecule was stably introduced into plants via the DNA-transfer mechanism of Agrobacterium tumefaciens. To date, the choice of 'interfering' molecule has been guided by empirical field-observations and each is effective against only a narrow range of closely-related viruses. As yet, we do not fully understand the molecular mechanism(s) responsible for the observed protection. The ability to manipulate the plant-pathogen relationship is a powerful tool to increase our knowledge and improve future strategies for unconventional cropprotection by genetic engineering techniques.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Jun
pubmed:issn
0265-9247
pubmed:author
pubmed:issnType
Print
pubmed:volume
10
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
179-86
pubmed:dateRevised
2005-11-16
pubmed:meshHeading
pubmed:year
1989
pubmed:articleTitle
Plant viruses: a tool-box for genetic engineering and crop protection.
pubmed:publicationType
Journal Article, Review