Linked Life Data

2662773

Source:http://linkedlifedata.com/resource/pubmed/id/2662773

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2
pubmed:dateCreated
1989-8-9
pubmed:abstractText
A case of hypocomplementemic membranoproliferative glomerulonephritis was studied during remission of nephrosis induced by high doses of corticosteroids. Hepatitis B surface antigen (HBsAg) and immune complexes were detected in serum and glomeruli. Anti-hepatitis-B surface antibody, undetectable in serum by conventional radioimmunoassays was identified in circulating immune complexes (CIC). On two occasions, improvement in renal function coincided paradoxically with an extreme increase in serum HBsAg levels as well as with marked elevation of CIC. We suggest that, as previously observed in animal models of glomerulonephritis, extreme antigen excess may inhibit glomerular deposition of immune complexes.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0250-8095
pubmed:author
pubmed:issnType
Print
pubmed:volume
9
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
162-6
pubmed:dateRevised
2007-2-14
pubmed:meshHeading
pubmed:year
1989
pubmed:articleTitle
Improvement of immune-complex nephritis associated with hepatitis B surface antigen excess.
pubmed:affiliation
Department of Medicine, Mount Scopus, Hadassah University Hospital, Jerusalem, Israel.
pubmed:publicationType
Journal Article, Case Reports, Research Support, Non-U.S. Gov't