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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:dateCreated |
1989-7-25
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pubmed:abstractText |
The body of this work illustrates the utility of the combined cytogenetic and molecular approach to lymphoid tumorigenesis. A number of tumor-specific translocations have proven amenable to dissection by molecular techniques. We have a firm grasp of the general principles that underlie lymphoid neoplasia; in particular, the activation of cellular oncogenes by translocation into genes of the immunoglobulin superfamily is a widespread phenomenon. However, numerous lymphopoietic malignancies are only poorly understood. These remain a challenge for the continued application of these methodologies.
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pubmed:grant | |
pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:issn |
0079-6603
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
36
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
269-80
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pubmed:dateRevised |
2007-11-14
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pubmed:meshHeading |
pubmed-meshheading:2660190-Base Sequence,
pubmed-meshheading:2660190-Burkitt Lymphoma,
pubmed-meshheading:2660190-Centromere,
pubmed-meshheading:2660190-DNA,
pubmed-meshheading:2660190-Humans,
pubmed-meshheading:2660190-Lymphoma,
pubmed-meshheading:2660190-Molecular Sequence Data,
pubmed-meshheading:2660190-Translocation, Genetic
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pubmed:year |
1989
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pubmed:articleTitle |
Molecular genetics of lymphoid tumorigenesis.
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.,
Review
|