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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
1
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pubmed:dateCreated |
1989-3-29
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pubmed:abstractText |
A study was performed to assess the effect of xylazine HCl (0.1 mg/kg of body weight, IV) in heifers maintained at thermoneutrality (18 C, 42% humidity) or under heat stress (33 C, 63% humidity) conditions. Xylazine caused 50 and 70% decreases in serum insulin concentrations in the thermoneutral and heat-stressed heifers, respectively. Xylazine-induced hypoinsulinemia was associated with hyperglycemia. In the thermoneutral group, serum glucose concentrations increased from a basal concentration of 75 mg/dl to 150 mg/dl after 15 minutes. In the heat stress group, the serum glucose concentration increased from 65 mg/dl to 105 mg/dl. Hyperglycemia peaked at 2 hours and remained high for 6 hours after xylazine administration. Heat-stressed heifers took a longer time (107 minutes) to stand than did heifers under thermoneutral conditions (41 minutes). The time to regain sensation to pain was significantly prolonged in heat-stressed heifers. Xylazine had no effect on body temperature and respiration rate in heifers under the thermoneutral condition, whereas it markedly induced hyperthermia and suppressed respiration rate in the heat-stressed heifers. Furthermore, the pulse rate was slightly decreased in thermoneutral heifers and was markedly decreased in the heat-stressed heifers.
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pubmed:grant | |
pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Jan
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pubmed:issn |
0002-9645
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
50
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
151-3
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pubmed:dateRevised |
2011-11-17
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pubmed:meshHeading |
pubmed-meshheading:2645815-Animals,
pubmed-meshheading:2645815-Blood Glucose,
pubmed-meshheading:2645815-Body Temperature,
pubmed-meshheading:2645815-Cattle,
pubmed-meshheading:2645815-Cattle Diseases,
pubmed-meshheading:2645815-Female,
pubmed-meshheading:2645815-Hot Temperature,
pubmed-meshheading:2645815-Insulin,
pubmed-meshheading:2645815-Pulse,
pubmed-meshheading:2645815-Respiration,
pubmed-meshheading:2645815-Stress, Physiological,
pubmed-meshheading:2645815-Thiazines,
pubmed-meshheading:2645815-Xylazine
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pubmed:year |
1989
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pubmed:articleTitle |
Effect of xylazine in heifers under thermoneutral or heat stress conditions.
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pubmed:affiliation |
Department of Dairy Science, University of Missouri-Columbia 65211.
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.,
Research Support, Non-U.S. Gov't
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