Linked Life Data

26253

Source:http://linkedlifedata.com/resource/pubmed/id/26253

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2
pubmed:dateCreated
1978-7-24
pubmed:abstractText
The presented results clearly demonstrate that theophylline, caffeine and theobromine have a blocking action on calcitonin effect as determined by the elevation of serum calcium level, although different degree of potency was found with each drugs. There is no difference in respect of the serum calcium elevation after a single dose of methyl xanthines or after a 9-10 day lasting treatment. The castration had no additional enhancing effect of the calcitonin resistance of methyl xanthine treated animals. The administration of androgens simultaneously with the methyl xanthine treatment failed to produce improvement of calcitonin sensitivty preventing the elevation of serum calcium after calcitonin injection. So the calcitonin resistance of methyl xanthine treated animals appears to be different to the calcitonin resistance of sex hormone deprived conditions because the latter could be abolished by androgen administration. Theophylline treatment resulted in a slightly but significantly elevated serum calcium comparing to controls without exogeneous calcitonin. This magnitude of elevation remains between the normocalcaemic limits.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Feb
pubmed:issn
0300-5704
pubmed:author
pubmed:issnType
Print
pubmed:volume
8
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
93-9
pubmed:dateRevised
2003-11-14
pubmed:meshHeading
pubmed:year
1978
pubmed:articleTitle
Influence of methyl xanthine treatment on calcitonin effect.
pubmed:publicationType
Journal Article