Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
5
pubmed:dateCreated
1981-8-10
pubmed:abstractText
The purpose of this paper is to present a brief coordinated overview of the recent results of research at the artery cell level which appear to have the greatest impact on the rapidly improving understanding of the pathogenesis of atherosclerosis in humans. The majority of these studies have employed in vitro methods and utilized the tools of modern cellular and molecular biology. These include microdissection; cell separation; tissue or cell culture; enzyme, lipid and protein chemistry as well as immunochemistry, ultrastructural visualization, cell organelle and membrane fractionation and the use of genetic markers. With these tools it is possible to study the interaction of the major space-occupying cells of the atherosclerotic plaque (especially the arterial smooth muscle cells) with many of the blood components, especially the lipoproteins and the other serum factors that appear to influence cell division. This direction of study appears to usher in a new era of atherosclerosis research.
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
May
pubmed:issn
0098-6127
pubmed:author
pubmed:issnType
Print
pubmed:volume
5
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
409-23
pubmed:dateRevised
2007-11-14
pubmed:meshHeading
pubmed:year
1979
pubmed:articleTitle
The emerging cellular pathobiology of atherosclerosis.
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, P.H.S.